Imaging in systemic amyloidosis

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Imaging in systemic amyloidosis.

BACKGROUND Diagnosis of systemic amyloidosis remains challenging. Histology, the current gold standard for diagnosis of amyloidosis provides limited information on the extent of the disease and is not useful for monitoring. Non-invasive imaging modalities offer an easy way to evaluate whole-body amyloid burden, accurately identify organ involvement, quantify and monitor disease progression and ...

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Cardiac magnetic resonance strain imaging in systemic light chain amyloidosis

Background Systemic light chain amyloidosis (AL) is associated with a high cardiovascular morbidity and mortality. Cardiovascular involvement and determination of prognosis is underestimated by standard imaging parameters. Recently, cardiac deformation analysis of global circumferential and longitudinal strain has been shown to have great clinical impact on the assessment of prognosis and survi...

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ژورنال

عنوان ژورنال: British Medical Bulletin

سال: 2013

ISSN: 0007-1420,1471-8391

DOI: 10.1093/bmb/ldt021